GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest rare disease data sets. For more information, please visit www.genedx.com.

As the Director, People Business Partner(Individual Contributor), you’ll be at the forefront of shaping our people strategy, leading with boldness, urgency, and a relentless focus on impact. You’ll report to the Sr. Director of People Experience, work closely with the Head of People and our Management Team, and set the pace for what’s possible in genomics leadership.

What You’ll Do

Mentor and inspire a high-performing People Business Partner (PBP) team, instilling the confidence, drive, and discipline it takes to lead—and win. Embed people experience tools and training into our DNA, ensuring every PBP is a trusted advisor and a catalyst for excellence.
Act as the direct PBP for a key business function, setting the standard for engagement and support. Build strong partnerships with management and the Executive Leadership Team, always pushing boundaries and driving solutions that redefine what’s possible for our people and our business.
Listen deeply to employees, leaders, and partners. Use data, feedback, and insights to deliver value at every touchpoint—because the experience depends on you. Ensure that people metrics are aligned with business goals and talent strategies. Champion change management, talent strategies, and people best practices that put our people and patients first.
Lead transformation initiatives that create ease, efficiency, and impact. Identify opportunities to improve, scale, and disrupt—moving fast and thinking beyond what’s comfortable. Use people data and analytics to craft compelling stories, influence decisions, and shape what’s next.
Drive change with clarity and conviction. Present data-driven insights that inform leadership decisions and drive meaningful, measurable results. Don’t wait for agreement—lead forward, challenge norms, and own the outcome.
Foster a culture of accountability, continuous learning, and high performance. Ensure the PBP team is aligned, equipped, and empowered to deliver with excellence. Balance autonomy with collaboration, and always follow through—because greatness is measured in results, not intentions.
Be direct, respectful, and open. Ask questions, share feedback, and grow together. Serve as a thought partner to leaders, anticipating and adapting to evolving workforce needs in a fast-paced, remote-first environment.

What You Will Bring

10+ years of progressive HR experience - always setting the pace and raising the bar.
Proven ability to build, develop, and inspire high-performing teams.
Experience as a strategic PBP, partnering with senior and executive leaders in complex, fast-evolving environments.
Relentless focus on data-driven insights, with the analytical skills to interpret trends and drive decisions.
Deep expertise in change management, organizational design, and leadership development.
Exceptional communication, relationship-building, and presentation skills—comfortable influencing at the highest levels.
Mastery of the HR landscape: performance management, talent management, compensation, employee relations, employment law, and a passion for diversity, equity, and inclusion.
Results-focused, deadline-driven, and unafraid to challenge the norm or synthesize complex information into bold, actionable solutions.
Ability to thrive in ambiguity, lead through transformation, and drive continuous improvement.
Comfort working autonomously and collaboratively, with a high degree of judgment and a bias for action.
Proficiency in MS Office Suite, especially Excel, with experience running and analyzing reports.
Willingness to travel up to 10% of the time.

#LI-REMOTE

Pay Transparency, Budgeted Range

$160,000—$175,000 USD

Science - Minded, Patient - Focused.

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most.

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:

Be bold in our vision & brave in our execution. 
Communicate directly, with empathy. 
Do what we say we're going to do.
Be adaptable to change.
Operate with a bias for action.

Benefits include:

Paid Time Off (PTO)
Health, Dental, Vision and Life insurance
401k Retirement Savings Plan
Employee Discounts
Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.

Director, People Business Partner

Related Jobs

Technical Director

Chief of Staff - REMOTE - SR005

Head of PMO

Partner Engagement Administrator - (Philadelphia, PA)

VP of Product

CPQuali - Estagiário em Pesquisa Clínica - Recrutamento

Consultancy Manager

Senior VP - Higher Education - MENA

CFO - MCE-NexGen - Brydon Portfolio Company

Chief Product Officer - Confidential Portfolio Company - The Brydon Group

Browse Similar Jobs