Technical Director
•SkydanceHybrid· 2d
✨ Other⏰ Full-time👔 Executive💰 $217k-246k🇺🇸 Santa Monica, USA
2d ago
Genomenoninc·11 days ago
Genomenon is an AI-driven biomedical intelligence company on a mission to save and improve lives by making biomedical information actionable. Rare diseases and cancer affect more than 30 million people in the U.S. alone and hundreds of millions globally, yet most patients still face long diagnostic journeys and limited treatment options. Our goal is clear and ambitious: to deliver the information that shapes diagnosis and treatment for every rare disease and cancer patient.
We sit at the intersection of AI, genomics, and real-world evidence. Genomenon transforms the global scientific literature into a literature-derived real-world evidence (RWE) engine for precision medicine—combining large-scale AI with expert human curation to deliver clean, clinically actionable datasets. This approach fills critical gaps left by EHR and claims data, especially in rare disease and oncology, by showing how patients actually present, progress, and respond to therapy.
We turn vast, complex biomedical data—spanning genomics, clinical evidence, and scientific literature—into trusted intelligence that helps clinicians make better diagnostic and therapeutic decisions, and supports life sciences organizations in bringing better therapies to market faster.
Our work has real, measurable impact. Genomenon’s platforms and services are used by more than 250 clinical laboratories and pharma organizations worldwide to support diagnostic interpretation, variant curation, and evidence-based decision-making across the drug development lifecycle.
Each year, our technology helps inform care for tens of thousands of patients facing rare, complex, and time-sensitive conditions—reducing uncertainty and delivering answers when they matter most.
What makes Genomenon unique is our ability to support both clinical diagnostics and pharmaceutical innovation on a shared foundation of advanced AI, deep domain expertise, and rigorously curated data.
If you’re motivated by impact, energized by complexity, and excited to help shape the future of rare disease diagnosis and treatment, there’s no better place to do that work.
Genomenon team members are thoughtful, ambitious, and mission-driven professionals working across states and countries. Our team brings together scientists, clinicians, engineers, and commercial leaders who collaborate as equals and learn from one another every day.
We value curiosity, accountability, and people who thrive in fast-moving, high-impact environments.
We are guided by our core values:
Genomenon is an AI-driven genomics company. Our mission is to save and improve lives by making genomic information actionable. We organize the world’s genomic knowledge and put it at the fingertips of clinicians and scientists to help diagnose and treat patients suffering from rare diseases and cancer.
Our flagship product, Mastermind, is a genomics intelligence platform that connects patient DNA to the scientific literature, accelerating clinical interpretation and precision medicine. We’re modernizing our commercial and internal software platforms to leverage AI-derived data, scalable APIs, and cloud-native architectures that support both customer-facing applications and internal clinical curation workflows.
This role is software engineering first. While it includes mentoring and light people management, the primary expectation is that you actively design, build, and ship production software. This position is best suited for an experienced, hands-on full stack engineer who enjoys leading by example and staying deeply engaged in day-to-day coding.
You are a senior, hands-on software engineer who enjoys building real products and leading through technical contribution. You have recent, meaningful experience writing production code and do not see management as a replacement for engineering, but as a complement to it.
You are comfortable moving between UI development, backend services, scripting, and automation, and you enjoy owning problems end to end. You communicate clearly, mentor thoughtfully, and enjoy translating complex technical systems into tools that support clinicians, scientists, and patients.
You are excited to modernize established software platforms, adopt AI-driven capabilities, and help define the next phase of clinical genetics software through direct technical leadership.
Building a great company starts with building a diverse and inclusive team. We believe that people with different backgrounds, perspectives, and life experiences help us solve harder problems and build better solutions.
Genomenon is committed to inclusion across race, gender, age, religion, identity, disability, and background — in how we hire, how we work, and how we lead.
If you’re excited about the role but unsure whether you meet every qualification, we encourage you to apply. We’d rather review one more resume than miss the chance to meet someone exceptional.