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Summary

The Associate Clinical Analyst II (ABMGG-eligible or active candidate) supports the interpretation of genetic findings and contributes to accurate diagnosis and case resolution through exome and genome sequencing. This entry-level role focuses on building foundational clinical analysis skills by assisting with case reviews under supervision, performing routine data interpretation tasks. Responsibilities include supporting variant classification activities, preparing accurate documentation, and contributing to internal database updates. The Associate Clinical Analyst II ensures timely documentation, maintains quality standards, and aids departmental initiatives through collaborative engagement and continuous learning.

Shift: Tuesday-Saturday or Sunday-Thursday 9am-5pm ET

How to Apply: Please submit your resume along with a cover letter (required for consideration) detailing your experience and motivation for applying. Applications without a cover letter will not be considered.

Job Responsibilities

• Perform clinical data analysis and case management to accurately interpret genetic findings.

• Establish phenotype-genotype correlations across diverse genetic disorders.

• Investigate and interpret clinical features of genetic conditions using internal resources and professional tools.

• Review and finalize genetic test reports, interpret variants, and curate internal databases.

• Serve as a subject matter expert for designated genes, disorders, tests, and workflows.

• Communicate with clients via email, phone, or other channels to support case resolution and provider engagement.

• May abstract clinical information from patient records.

• Performs literature reviews and database searches to support variant interpretation and classification.

• Meets or exceeds productivity and error standards as assigned by team lead.

• Documents evidence and rationale for variant classification in a clear, standardized format.

• Assist with development of variant-, gene-, or disease-specific test information and report language.

• Perform other duties as assigned to support the team or department.

• Credential-specific responsibilities include but are not limited to:

• ABMGG Certified: Fulfill responsibilities of Clinical Consultant as defined by CLIA (42 CFR 493.1457), including:

• Consultation Availability: Provides timely consultation to ordering providers regarding test selection, interpretation, and clinical correlation of laboratory results.

• Report Oversight: Reviews and ensures laboratory reports meet CLIA and CAP requirements for accuracy, completeness, and clinical relevance.
• Result Authorization: Approves and signs off on high-complexity test results in accordance with CLIA regulations.

Education, Experience, and Skills

• PhD in Biology, Genetics or related field, MD or DO with more than 2 years directly relevant experience in clinical diagnostics (including fellowship)

• Excellent verbal and written communication skills

• Demonstrated computer skills, including ability to maintain high proficiency with internal systems and Microsoft Office Suite and the Office 365 environment

• Prior experience with variant curation is preferred but not required

Certificates, Licenses, Registrations

• ABMGG certification or equivalent, certified in at least one specialty OR board eligible

Physical Demands

• Prolonged periods of sitting or working at a computer in a home office environment

• Occasional need to lift or move materials or equipment weighing up to 20 pounds during travel or team visits

Work Environment

• Frequent use of digital communication platforms (e.g. video conferencing, email, and collaboration tools).

• Ability to focus and manage complex tasks in a remote setting with multiple concurrent priorities.

• May require occasional travel to laboratory sites, corporate offices, or conferences (typically <10%).

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