Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer.

At Iovance Biotherapeutics, the Manager, TIL Therapy Case Management (Individual Contributor) plays a critical role in supporting patients navigating treatment with tumor-infiltrating lymphocyte (TIL) therapies, including Amtagvi. This position is a senior individual contributor responsible for managing complex, time-sensitive patient cases and serving as a subject matter expert on TIL therapy workflows. The role partners closely with patients, caregivers, and authorized treatment centers to coordinate each step of the treatment journey—from tumor procurement through infusion.

Essential Functions and Responsibilities

• Manage end-to-end patient cases for TIL therapy from referral through post-infusion
• Serve as a primary contact and trusted advisor for patients and providers
• Provide expertise on TIL therapy workflows including tumor procurement and manufacturing coordination
• Collaborate with treatment centers and interdisciplinary care teams
• Partner with internal teams to ensure alignment across time-sensitive milestones
• Identify and resolve barriers to therapy access
• Track critical milestones across the autologous treatment process
• Support site onboarding and share best practices
• Contribute to continuous improvement initiatives
• Maintain current knowledge of and follow established IovanceCares objectives, processes, regulatory and compliance standards, policies, and procedures.
• Demonstrate genuine passion and care for patients and uphold Iovance values in daily individual work performance.
• Adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business
• Perform miscellaneous duties as assisgned.

Travel

• Be available to occasionally travel during the site onboarding process or as needed (<10%).

Required Education, Skills, and Knowledge

• Bachelor’s degree or equivalent experience
• 6+ years of relevant healthcare or biopharma experience
• Direct experience with TIL therapy (e.g., Amtagvi) or closely related workflows
• 2+ years of case management or care coordination in oncology
• Ability to manage complex, time-sensitive cases independently
• Strong communication and organizational skills
• Ability to work across matrixed teams

Preferred Education, Skills, and Knowledge

• Experience supporting Amtagvi or other cell therapies
• Clinical background (e.g., RN, NP, PA, PharmD, MSW)
• Experience in solid tumor oncology
• Familiarity with manufacturing-dependent therapies
• Experience in patient access and reimbursement
• Experience in regulated environments
• Multilingual skills (e.g., Spanish)

The physical demands described here represent those that an employee must meet to perform the essential functions of this job successfully. Reasonable accommodation may be made upon request to enable an individual to perform essential functions. Please contact Human Resources to request accommodation.

Physical Demands and Activities Required

• Must be able to remain in a stationary position standing or sitting for prolonged periods of time.
• Must be able to move about inside an office and exert up to 10 pounds of force occasionally or a negligible amount of force frequently or constantly to lift, carry, push, pull, or otherwise move objects.
• Must have visual acuity to perform activities such as preparing and analyzing data and figures, viewing a computer screen, and extensive reading.
• This position requires repetitive motion, substantial movements (motions) of the wrist, hands, and/or fingers.
• Must be able to communicate with others to exchange information.

Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously; and ability to meet deadlines

Work Environment

This job operates in a professional workplace or remote office environment and requires standard office equipment and keyboards. Employees who work remotely are expected to maintain their workspace and environment safely and free from safety hazards.

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