Director, Medical Value & Outcomes (MVO)

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

The Director, Medical Value & Outcomes (MVO) is a highly trained, field-based scientific expert responsible for engaging healthcare professionals and external decision makers through the exchange of clinical, scientific, economic, and research information related to Mineralys’ products and pipeline. The Director, MVO establishes, cultivates, and maintains professional relationships with key stakeholders—including healthcare professionals (HCPs), medical thought leaders, payors, managed care organizations, integrated delivery networks, and government entities.

In close partnership with the Market Access team, the Director, MVO supports strategic and tactical engagement with payors and key population-health decision makers. All activities are conducted in a scientifically objective and compliant manner, consistent with local, state, and national regulations, and industry guidelines.

This role functions as a core member of the Field Medical Affairs team and as a cross-functional collaborator who provides therapeutic area expertise, communicates value-based evidence, and delivers actionable insights to internal stakeholders.

Key Responsibilities

• Serve as a primary field-based scientific subject matter expert supporting Medical Affairs and Market Access, providing therapeutic area, clinical, economic and product expertise.
• Build, cultivate, and enhance professional relationships with key payor and population health decision makers across regions and geographies.
• Provide scientific and clinical support to the Market Access team in alignment with strategic medical and corporate objectives.
• Engage in evidence-based clinical and economic discussions with payor stakeholders, including formulary decision makers, medical directors, and pharmacy directors.
• Develop a tactical, customer-centric medical engagement plan aligned with leadership direction.
• Provide timely, accurate clinical, scientific, and economic updates—proactively or in response to unsolicited requests—per SOP, including support related to value dossiers and evidence materials.
• Demonstrate strong knowledge of value evidence and how payors utilize clinical, economic, and humanistic evidence in access, reimbursement, and adoption decisions.
• Contribute to the development of value evidence generation plans, ensuring alignment with evolving payer needs.
• Identify real-world evidence (RWE) opportunities based on payer insights and communicate these opportunities to internal cross-functional teams.
• Provide medical support at selected scientific congresses, including attending sessions, supporting the medical information booth, conducting debriefs, and preparing post-congress summaries for internal stakeholders.
• Gather, interpret, and communicate key customer insights to inform internal strategy, evidence development, and product planning.
• Ensure all activities comply with company policies, procedures, and applicable regulations (e.g., FDA, OIG, OSHA, PhRMA, etc.).

Education, Experience & Skills Requirements

Required Qualifications

• PharmD, PhD, MD, DO, (or other doctoral degrees considered)
• Minimum 7 years of U.S. field-based pharmaceutical experience in roles such as:
  • Medical Value & Outcomes
  • Field HEOR / payer-facing scientific liaison
  • Medical Science Liaison with direct payer engagement
  • Market Access–aligned field medical roles
• Demonstrated, recent experience engaging payors (health plans, PBMs, integrated systems, government programs, employer groups, international payer bodies) in scientific, clinical, or economic discussions.
• Proven ability to conduct evidence-based scientific exchange with payer decision makers through in-person and virtual interactions.

Travel

Travel approximately ~20–30%, including domestic and occasional international travel to scientific congresses, investigator meetings, advisory boards, field team visits, Medical Affairs planning sessions, and cross-functional onsite meetings.

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range: $225,000 - $240,000

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