Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis Precision Medicines is entering a pivotal moment as we prepare for commercialization, and how we build and scale capability across the organization will directly impact our success.
We are seeking a strategic and visionary Area Vice President of Sales to lead execution and drive commercial performance across key markets. This leader will be responsible for building, scaling, and leading high-performing sales and account management teams while ensuring alignment with enterprise commercial strategy.

Working closely with senior leadership, you will help architect a modern, agile field organization that is operationally excellent, customer-focused, and built to support successful product launches and sustained growth.

Primary Responsibilities

• Lead and develop regional sales and account management teams to deliver strong performance and achieve commercial objectives.
• Drive execution of a unified commercial strategy across geographies in alignment with enterprise priorities.
• Oversee strategic account engagement, including health systems, IDNs, IPNs, and key payer relationships.
• Partner closely with Commercial, Medical Affairs, Patient Services, and Market Access to deliver coordinated customer engagement.
• Drive field readiness and execution across pre-launch, launch, and post-launch phases for multiple products.
• Ensure sales teams are equipped with the capabilities, tools, and behaviors required for successful product launches.
• Build scalable processes, infrastructure, and performance management systems to support growth.
• Establish clear metrics to measure effectiveness and drive continuous improvement across the field.
• Recruit, develop, and retain top talent while building a high-performance, accountable culture.
• Provide insights from the field to inform strategy, execution, and future capability development.

How You Work

• You think in systems, not silos.
• You balance rigor with speed, knowing when each matters most.
• You hold a high bar for performance, quality, and accountability.
• You collaborate deeply but act with ownership and urgency.
• You are passionate about building scalable, sustainable commercial capabilities.

What You Bring

• 15+ years of progressive experience in pharmaceutical sales and commercial leadership, including direct management of regional or national sales teams.
• Prior VP or Director-level experience in rare disease or CNS preferred.
• Proven track record of leading strategic account and health system engagement at a national or regional level.
• Deep understanding of IDN, IPN, and payer dynamics in rare disease and specialty markets.
• Demonstrated experience owning a full national or multi-regional product launch in rare disease, CNS, or specialty pharmaceuticals.
• Experience leading cross-functional commercial teams through pre-launch, launch, and post-launch phases.
• Background building and leading commercial organizations within biotech or emerging pharmaceutical companies.
• Ability to build scalable infrastructure, attract top talent, and deliver results in high-expectation environments.
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. This range reflects the base salary the Company reasonably expects to pay for the position at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.