Director Commercial FP&A

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis Medicines is seeking a Commercial FP&A leader to serve as a strategic finance partner to our Commercial organization as we prepare for launch and scale toward a multi-billion-dollar revenue organization. This role will support near-term launch readiness while also building the financial capabilities, discipline and insights required to operate at commercial scale over time.

This role sits within Finance but works in close, real-time partnership with Commercial, CMC and other cross-functional teams. The successful candidate will be deeply embedded in ongoing commercial workstreams, enabling forward-looking decision-making through continuous engagement rather than periodic reporting.

Primary Responsibilities

• Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
• Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi-billion-dollar revenue levels.
• Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
• Collaborate cross-functionally on pricing, gross-to-net, market access and demand dynamics.
• Lead Commercial and CMC input into budgets, ongoing forecasts and long-range plans.
• Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
• Develop executive-ready materials that clearly communicate risks, opportunities and trade-offs.
• Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.
  
  

Qualifications and Key Success Factors

• 12–15+ years of experience in FP&A or strategic finance, with strong commercial exposure
• Biopharma experience required, including experience supporting a commercial-stage company
• Experience supporting product launch and operating in a scaled commercial environment preferred
• Advanced financial modeling and analytical skills
• Proven ability to influence and partner with senior stakeholders across Finance, Commercial and CMC
• Strong business judgment and executive communication skills
• Comfortable operating in a fast-paced, evolving environment with ambiguity
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience.